Mouse Spermatogenesis Requires Classical and Nonclassical Testosterone Signaling1

Non-classical actions of testosterone and spermatogenesis.

Testosterone is essential to maintain spermatogenesis and male fertility. In the absence of testosterone stimulation, spermatogenesis does not proceed beyond the meiosis stage. After withdrawal of testosterone, germ cells that have progressed beyond meiosis detach from supporting Sertoli cells and die, whereas mature sperm cannot be released from Sertoli cells resulting in infertility. The clas...

Classical and Nonclassical Logics

Schechter, Eric, 1950– Classical and nonclassical logics : an introduction to the mathematics of propositions / Eric Schechter. p. cm. Includes bibliographical references and index. British Library Cataloging-in-Publication Data is available The publisher would like to acknowledge the author of this volume for providing the camera-ready copy from which this book was printed.

Suppression of human spermatogenesis by testosterone implants.

Hormonally induced azoospermia is an effective, reversible form of male contraception; however, some men treated with weekly im testosterone enanthate (TE) injections fail to become azoospermic. As weekly injections cause widely fluctuating and supraphysiological testosterone levels, we tested the hypothesis that more stable, physiological testosterone levels would consistently produce azoosper...

A Classical Physics Review for Nonclassical Physics

A classical view on nonclassical nucleation.

Understanding and controlling nucleation is important for many crystallization applications. Calcium carbonate (CaCO3) is often used as a model system to investigate nucleation mechanisms. Despite its great importance in geology, biology, and many industrial applications, CaCO3 nucleation is still a topic of intense discussion, with new pathways for its growth from ions in solution proposed in ...